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MASCC Oral Care Study Group

Chair: Siri Beier Jensen, DDS,PhD - Denmark
Co-chair: Deborah P. Saunders, BSc, DMD - Canada
Co-chair: Tuomas Waltimo, DDS,PhD - Switzerland

Study Group Minutes
2014 Minutes alt - Miami, Florida

The Oral Care Study Group’s major goals are to enhance knowledge of the wide range of oral complications associated with cancer therapies and to support the translation into improved clinical management for patients. The group’s objectives are to understand the clinical impact of the wide variety of oral complications. These include xerostomia, dysgeusia, dysphagia, oral pain, fungal infection, viral infection, osteoradionecrosis, osteonecrosis from bisphosphonates, dental disease and trismus.

The Study Group aims to develop and coordinate new evidence-based management guidelines. In addition, the Oral Care Study Group serves as a resource for collaborative research efforts among members of this group as well as other members of MASCC and ISOO. Another focus of the Oral Care Study Group is education for members of MASCC and ISOO. The group will undertake multiple, systematic reviews of the incidence and prevalence or oral complications of cancer therapy, as well as their management, effects on quality of life, and economic impact. Efforts are underway to establish a multicenter study of members of the Oral Care Study group to prospectively collect data on various outcomes related to oral complications of cancer therapy.

MASCC Study Group Chairs Leading Study on Oral Complications of Radiotherapy
Dr. Michael Brennan and Dr. Raj Lalla are the Co-Principal Investigators of an NIH-funded study, Treatment Outcomes from Head and Neck Cancer Therapies. An award of $8 million was made, in 2012, to Carolinas HealthCare System (CHS) to conduct a multi-center study.

The research team is studying dental and oral medicine outcomes among patients who have received high-dose radiation to the head and neck region. These outcomes include a permanent decrease in saliva production (hyposalivation) and impaired healing of bone around the teeth (osteoradionecrosis), adverse effects with a major impact on quality of life and risk for further dental complications.

Dr. Brennan is the current President of the International Society of Oral Oncology and recently served as the Chair of the Oral Care Study Group of MASCC. Dr Lalla is the current Chair of the MASCC Mucositis Study Group and also is a MASCC Board Member.  Read More>> alt




Clinical Research Initiative
Diagnostic and Management Practices for Oral Chronic Graft-Versus-Host Disease (cGVHD)
The Oral Care Study Group conducted a study on the diagnosis and treatment of oral chronic graft-versus-host disease (cGVHD). The study was designed to assess common practices, as well as to determine use of the National Institute of Health scale for the diagnosis and grading of oral cGVHD. The project was headed by Sharon Elad, DMD, MSc, Eastman Institute for Oral Health, University of Rochester Medical Center.

A survey was distributed to Oral Care Study Group and MASCC/ISOO members in order to identify medical centers with experience in managing patients with oral cGVHD. The structured survey contained questions about the respondents’ demographics, whether or not they treat oral cGVHD, evaluation tools, diagnostic aids, topical treatments, and preventive measures. Read more>>

Summary of the Oral Complications Systematic Reviews (alt PDF, 140 KB)

Management Recommendations - Summary of Evidence Table (alt PDF, 64 KB)

Evidence-Based Management Strategies for Oral Complication from Cancer Treatment
 - Oral Care Study Group, MASCC/ISOO.  (This is a large file, for assistance email (PPT, 4.7 MB) )



Oral ComplicationsOral Complications of Cancer and its Management  - Edited by Andrew Davies and Joel Epstein, 20% Member Discount. Brought to you through MASCC's bookclub from Oxford University Press

Books on Supportive Care  >>VIEW ALL - MASCC Member Discount

Related Links

Mouth Cancer Foundation
National Cancer Institute information on Oral Mucositis


MASCC Study Group Coordinator, Anne Young

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