Mucositis Guidelines
A major recent effort of the Mucositis Study Group of MASCC/ISOO has been a comprehensive review of the literature related to mucositis and the development of evidence-based clinical practice guidelines. The first set of MASCC/ISOO Mucositis Guidelines were based on literature published between January 1996 and May 2002. The original guidelines were published in the journal Cancer in 2004. In June 2005, panelists from the Mucositis Study Group met again to update these guidelines. These updates were based on a comprehensive and systematic evaluation of the literature published since May 2002. The updated guidelines were published in the journal Cancer in 2007. A link is provided below to free full text of the manuscript describing the updated guidelines.
Updated clinical practice guidelines for the prevention and treatment of mucositis.
Keefe DM, Schubert MM, Elting LS, Sonis ST, Epstein JB, Raber-Durlacher JE, Migliorati CA, McGuire DB, Hutchins RD, Peterson DE; Mucositis Study Section of the Multinational Association of Supportive Care in Cancer and the International Society for Oral Oncology.
Cancer. 2007 Mar 1;109(5):820-31.
The following document is a German translation of the updated guidelines.
German Translation
Mucositis Guidelines (Update 2006, dt.Version) (91K)
Mucositis Guidelines (123K)
Summary Tables of Guidelines
The updated guidelines are summarized in the tables below:
Mucositis: Perspectives and Clinical Practice Guidelines Table
MASCC/ISOO Summary Guidelines Table 
MASCC/ISOO Summary Guidelines Table
Greek Translation
MASCC/ISOO Summary Guidelines Table
MASCC/ISOO Summary Guidelines Table
As an outcome of the guidelines update, The Mucositis Study Group also published several papers in the Society Journal, Supportive Care in Cancer, in June 2006. These papers provide detailed information on the evidence underlying the development of the updated guidelines for each category of clinical agent. The link below provides free access to full-text of all of these articles.
Mucositis-related articles from the Mucositis Study Group, published June 2006.
The links below provide free full-text access to the papers summarizing the original guidelines, published in 2004.
Perspectives on cancer therapy-induced mucosal injury: Pathogenesis, measurement, epidemiology, and consequences for patients (p 1995-2025)
Stephen T. Sonis, Linda S. Elting, Dorothy Keefe, Douglas E. Peterson, Mark Schubert, Martin Hauer-Jensen, B. Nebiyou Bekele, Judith Raber-Durlacher, J. Peter Donnelly, Edward B. Rubenstein
Published Online: 19 Apr 2004
Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis (p 2026-2046)
Edward B. Rubenstein, Douglas E. Peterson, Mark Schubert, Dorothy Keefe, Deborah McGuire, Joel Epstein, Linda S. Elting, Philip C. Fox, Catherine Cooksley, Stephen T. Sonis
Published Online: 19 Apr 2004
Guidelines-related Meeting Presentations
The current version of the guidelines was first presented at the 2005 MASCC/ISOO meeting
Mucositis Management Guidelines
Dorothy Keefe
MASCC/ISOO 17th International Symposium - Geneva, June 2005
View PDF Presentation
Practical implementation of these guidelines was also discussed at the 2004 MASCC/ISOO meeting.
Dorothy M.K. Keefe, Michael Brennan,Inger von Bultzingslowen, Mark M. Schubert
MASCC/ISOO 16th International Symposium - Miami, June 2004
View PDF Presentation
View PDF Summary
