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MASCC Skin Toxicity Study Group
The mission of the MASCC Skin Toxicity Study Group is to develop research and management strategies for skin conditions due to cancer or anticancer drugs. Skin reactions are frequent in those affected by cancer. They can reduce quality of life and require modifications in lifesaving antineoplastic therapy. This interdisciplinary Study Group aims to raise awareness of dermatological conditions in cancer patients and take a leadership role in the emerging field of cancer-related skin toxicities management.
The objectives of the Skin Toxicity Study Group include the following:
Key efforts are directed toward the identification of phenotypes and treatment regimens with a higher risk, as well as preventive measures and early intervention as standards of care. This Study Group also serves as a resource for multicenter clinical trials and translational studies.
Guidelines & Assessment Tools
Lacouture ME, Anadkat MJ, Bensadoun RJ, Bryce J, Chan A, Epstein JB, et al; for MASCC Skin Toxicity Study Group. Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities. Support Care Cancer. 2011 Aug;19(8):1079-95.
MASCC appreciates the unrestricted grants from BMS, EvoLife, OSI, and Amgen.
Subsequently, a CME-certified slide set was developed, in which Dr. Lacouture provides a case-based review of the MASCC guidelines for preventing and treating dermatologic toxicities in patients receiving EGFR inhibitors:
EGFR Inhibitor–Related Dermatologic Toxicities: Applying MASCC Guidelines in Prevention and Treatment
MASCC EGFR Inhibitor Skin Toxicity Tool© (MESTT) (1.1MB ppt)
Caring for your skin, hair and nails on "Targeted Therapies" - Download this brochure for patients with EGFRI side effects.
Predicting Diarrhea and Rash in Breast Cancer Patients Treated with Lapatinib and Capecitabine
Clinical practice guidelines for the prevention and treatment of acute and late radiation reactions from the MASCC Skin Toxicity Study Group. Supportive Care in Cancer October 2013, vol 21, #10
Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities. Supportive Care in Cancer, Volume 19, Number 8, 1079-1095, DOI: 10.1007/s00520-011-1197-6. Mario E. Lacouture, Milan J. Anadkat, René-Jean Bensadoun, Jane Bryce, Alexandre Chan, Joel B. Epstein, Beth Eaby-Sandy, Barbara A. Murphy and MASCC Skin Toxicity Study Group
Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients Mario E. Lacouture. 2014
Dr. Lacouture's Skin Care Guide for People Living With Cancer - Written by MASCC Member, Dr. Mario Lacouture, an expert in the dermatologic side effects of anti-cancer medications. this book offers clear information and practical suggestions for preventing, treating, and living through these skin, hair, and nail changes.
Please contact the Study Group Chairs above with your questions.