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2015 MASCC/ISOO Annual Meeting Study Group Workshops

Past Workshops:  2016  |   2015  |  2014  |  2013  |  2012  |  2011

The 2015 MASCC/ISOO Annual Meeting in Copenhagen featured five in-depth Pre-Conference Workshops. These workshops, sponsored by several Study Groups, provided an opportunity for participants to hear about the latest research and to meet colleagues with similar interests.

Mucositis Research 
The Mucositis Study Group presented a workshop with a focus on the latest advances in mucositis research. This event, designed to offer an informal venue for detailed discussion and to promote collaboration, included two sessions: pre-clinical and clinical. The first included presentations of basic research aimed at the management of cancer therapy-induced mucositis. The clinical session focused on management of chemoradiotherapy-induced mucositis in patients with oropharyngeal carcinoma, treatment of oral mucositis in children and adults, and pain management for head and neck cancer patients with oral mucositis. The sessions included the following presentations.

Pre-Clinical Session

  • Jean-Luc Mougeot (USA). Cancer Therapy-Induced Oral Mucositis: In Silico Drug Discovery Based on Molecular Pathway Interactions Between Oral Mucosa and Oral Microbiome
  • Nicoline Kuiken (Netherlands). Minimal Enteral Feeding Improves Recovery of Methotrexate-Induced Gastrointestinal Mucositis in the Rat
  • Bronwen Mayo (Australia). Microbial Alterations and Toll-Like Receptor Expression Play a Role in the Improvement of Irinotecan-Induced Mucositis After Treatment with the New Selective GLP-2 Receptor Agonist, Elsiglutide
  • Ysabella van Sebille (Australia). Characterization of Dacomitinib-Induced Diarrhea: Targeting Chloride Secretion with Crofelemer
  • Hannah Wardill (Australia). Irinotecan-Induced Pain Is Associated with Central Astrocyte Activation in Mice with Severe Gut Toxicity
  • Suzanne Mashtoub (Australia). Emu Oil Source Does Not Significantly Alter Therapeutic Efficacy, Whilst Ostrich Oil Has No Beneficial Effect, in a Rat Model of Chemotherapy-Induced Mucositis

Clinical Session

  • Carryn Anderson (USA). Phase 1 Trial of Superoxide Dismutase Mimetic GC4419 to Reduce Chemoradiotherapy-Induced Mucositis in Patients with Mouth or Oropharyngeal Carcinoma
  • Alessandra Majorana (Italy). Clinical Efficacy of a Medical Device in the Treatment of Chemotherapy-Induced Oral Mucositis in Children
  • Dimitra Galiti (Greece). Oral Candida Carriage, Oral Mucositis, Pain and Xerostomia and Quality of Life in Head and Neck Cancer Patients, Following IMRT
  • Ina Seidenspinner (Germany). Effects of Episil® Oral Liquid in Cancer Patients with Oral Mucositis: An Observational Study
  • Stine Mogensen (Denmark). New Bupivacaine Lozenge as Pain Management for Head and Neck Cancer Patients with Oral Mucositis
  • Reddy Belum (USA). Oral Lichenoid Lesions During Treatment with PD-1/PD-L1 Pathway Inhibitors

Advances in Cancer-Related Fatigue: A Focus on Patients with Advanced Cancer 
Chaired by Sriram Yennu, Karin Olson, and Mellar Davis

The Fatigue Study Group, the Palliative Care Study Group, and the Rehabilitation, Survivorship and Quality of Life Study Group jointly offered this workshop on cancer-related fatigue (CRF), the most common and debilitating symptom in patients with advanced cancer. Workshop participants focused on the latest research and knowledge regarding the assessment, subtypes, mechanisms, and management of advanced cancer patients with CRF. Presentations covered targeted-therapy-related CRF, biomarkers, the role of physical activity in the improvement of CRF and function, integrative and  psychological interventions, and future directions in pharmacological treatment trials. 

  • Sriram Yennu (USA) and Mellar Davis (USA). Introduction
  • Karin Olson (Canada). Assessment of CRF and Its Subtypes in Advanced Cancer
  • Mellar Davis (USA) and Leorey Saligan (USA). The Latest Advances With Regards to Understanding of the Underlying Mechanisms of CRF With Focus on Targeted Therapy Related CRF and Biomarkers
  • Karen Mustian (USA). Review of the Role of Physical Activity in Improvement of CRF and Function in Advanced Cancer: Implications for Clinical Practice and Research
  • Debra Barton (USA). Integrative and Psychological Interventions and Their Impact on CRF
  • Eduardo Bruera (USA). Future Directions in Pharmacological Treatment Trials for CRF in Advanced Cancer
  • Sriram Yennu (USA). Case Study Presentations

Dysphagia Burden of Illness: An Underreported Complication of Treatment
Chaired by Siri Beier Jensen (Denmark), Liz Isenring (Australia), Barbara Murphy (USA), Paolo Bossi (Italy)

The Nutrition and Cachexia Study Group and the Oral Care Study Group jointly sponsored this pre-conference workshop on this long-term adverse effect of cancer therapy. It is well recognized that many patients develop dysphagia subsequent to head and neck cancer therapy, but its long-term effects are less understood. The workshop considered dysphagia in head and neck cancer patients, during and after treatment. Topics included oral problems (dental health, mastication, and xerostomia), measurement issues (objective vs. subjective measures), swallow therapy, nutritional management, nutraceuticals, conformal radiotherapy, and low-energy laser therapy, as well as an update on relevant literature. The workshop included the following presentations.

  • Elvio Russi (Italy). Dysphagia Burden of Illness: An Underreported Complication of Treatment 
  • Joel Epstein (USA). Oral Issues: Dental Health, Mastication and Xerostomia
  • Sara Vinther Fredslund (Denmark). Measurement Issues: Patient Reported Versus Objective Measures 
  • Barbara Murphy (USA). The Role of Swallow Therapy: What, When and How Much? 
  • Liz Isenring (Australia). Nutritional Management of the Patient with Head and Neck Cancer
  • Wolf Marx (Australia). Is There a Place for Nutraceuticals in Patients with Dysphagia? Review of Trends and Evidence.
  • Anthony Cmelak (USA). Conformal Radiotherapy Techniques: Minimization of Dysphagia Late Effect 
  • Rene-Jean Bensadoun (France). Low Energy Laser for Dysphagia Prevention and Treatment: Which Role and Evidence?
  • Barbara Murphy (USA) and Paolo Bossi (Italy). Presentation of Selected Abstracts About Dysphagia and Update of the Systematic Review of the Literature
  • Siri Beier Jensen (Denmark), Dr. Barbara Murphy (USA). Conclusions, Trials in Progress and Next Steps 

Anemia in Cancer
Chaired by Bernardo Rapoport (South Africa), Jean Klastersky (Belgium), Marianne van de Wetering (The Netherlands)

The Neutropenia, Infection, and Myelosuppression Study Group and Pediatrics Study Group jointly sponsored this workshop to provide an update and an overview of anemia in adult and pediatric patients with cancer. The program included blood transfusions, the role of erythropoetin, and guidelines for anemia in children with cancer. Topics pertaining to anemia in adult patients included basic mechanisms, anemia in patients with solid tumors and hematological malignancies, treatments, and current guidelines. The workshop also provided an opportunity to discuss controversial issues related to these topics. 

Pediatric Session

  • Marianne van de Wetering (The Netherlands). Case Presentation: What to Do If Blood Transfusions Are Not Allowed in a Pediatric Oncology Patient
  • Jakica Tancabelic (USA). The Role of Erythropoetin in Children with Cancer
  • Erik Loeffen (The Netherlands). Guidelines for Anemia in Children with Cancer

Adult Session

  • Devan Moodley (South Africa). Basic Mechanism
  • Bernardo Rapoport (South Africa). Anaemia in Patients with Solid Tumours and Haematological Malignancies
  • Georgia Demetriou (South Africa). Differential Diagnosis and Workup of the Cancer Patient Presenting with Anaemia
  • Jean Klastersky (Belgium). Treatment of Anaemia (Including Transfusions, Role of IVI Iron and the Role of ESAs)
  • Matti Aapro (Switzerland). Current Guidelines Overview
  • Mario Dicato (Luxembourg). Overview of Studies Looking at a Decrease in Survival
  • Debate: Cancer and Quality of Life - Ronald Feld (Canada). Against ESAs, Rekha Parameswaran (USA). In Favor of ESAs 

Educational Challenges: Strategies to Provide Excellent Cancer Care to Underserved Populations
Chaired by Manon Lemonde (Canada), Niharika Dixit (USA), Gregory Crawford (Australia), M. Paz Fernandez-Ortega (Spain), Judy Phillips (USA), Faith Ottery (USA), Massey Nematollahi (Canada)

The Education Study Group sponsored this workshop on the needs of underserved populations worldwide. Such populations include those underserved because of age, race, disabilities, gender/sexual orientation. geographic isolation or limitations, language, literacy, refugee or immigrant status, or socioeconomic instability. As part of this workshop, the group discussed the results of the Study Group’s survey on cancer care for underserved populations.

  • Manon Lemonde (Canada). Introduction and Results of the Survey
  • Niharika Dixit (USA). Gregory Crawford (Australia), M Paz Fernandez-Ortega. Discussion  of What “Underserved Populations’ Means and Share Real-Life Experience with These Patients, Including Background and Needs: North American, Australian, and European Perspectives
  • Sora Park Tanjasiri (USA). Discussion of the Educational Challenges Which Cover the Emotional, Psychosocial and Physical Challenges the Underserved Patients Face (Hearing Loss, Literacy, Language Barriers, Mental Illness)
  • Judy Phillips (USA), Faith Ottery (USA). Health Literacy: Impediments to Effective Communication, e.g., Readability, Literacy, and Cultural Sensitivities
  • Manon Lemonde (Canada). Community-Based Participatory Research
  • Niharika Dixit (USA), Judy Phillips (USA), Massey Nematollahi (Canada). Discussion About Potential Education Interventions