Recent Publications by Members of the Nutrition & Cachexia Study Group

Enteral and parenteral nutrition in cancer patients, a comparison of complication rates: an updated systematic review and (cumulative) meta-analysis. Chow R, Bruera E, Arends J, Walsh D, Strasser F, Isenring E et al. Support Care Cancer. 2019 Dec 7. [Epub ahead of print]. (Erratum in: Support Care Cancer. 2019 Dec.)

Eating As Treatment (EAT): A Stepped-Wedge, Randomized Controlled Trial of a Health Behavior Change Intervention Provided by Dietitians to Improve Nutrition in Patients With Head and Neck Cancer Undergoing Radiation Therapy (TROG 12.03). Britton B, Baker AL, Wolfenden L, Wratten C, Bauer J, Beck AK, McCarter K, Harrowfield J, Isenring E, Tang C, Oldmeadow C, Carter G. Int J Radiat Oncol Biol Phys. 2019 Feb 1;103(2):353-362.

Lipid metabolism in cancer cachexia. Dalal S. Ann Palliat Med. 2019 Jan;8(1):13-23.

Measuring cachexia-diagnostic criteria. Dev R. Ann Palliat Med. 2019 Jan;8(1):24-32.

Health-related quality of life across cancer cachexia stages. Kasvis P, Vigano M, Vigano A. Ann Palliat Med. 2019 Jan;8(1):33-42.

What are the criteria for response to cachexia treatment? Crawford J. Ann Palliat Med. 2019 Jan;8(1):43-49.

A hunger for hunger: a review of palliative therapies for cancer-associated anorexia. Childs DS, Jatoi A. Ann Palliat Med. 2019 Jan;8(1):50-58.

Combination therapy in cachexia. Del Fabbro E. Ann Palliat Med 2019;8(1):59-66.

Prokinetics and ghrelin for the management of cancer cachexia syndrome. Malik JS, Yennurajalingam S. Ann Palliat Med. 2019 Jan;8(1):80-85.

Sarcopenia associated with chemotherapy and targeted agents for cancer therapy. Davis MP, Panikkar R. Ann Palliat Med. 2019 Jan;8(1):86-101.

Multicentre factorial randomized clinical trial of perioperative immunonutrition versus standard nutrition for patients undergoing surgical resection of oesophageal cancer. Mudge LA, Watson DI, Smithers BM, Isenring EA, Smith L, Jamieson GG; Australian Immunonutrition Study Group. Br J Surg. 2018 Sep;105(10):1262-1272.

Cancer cachexia: rationale for the MENAC (Multimodal-Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial. Solheim TS, Laird BJA, Balstad TR, Bye A, Stene G, Baracos V, Strasser F et al. BMJ Support Palliat Care. 2018 Sep;8(3):258-265. Review.

Evaluating the effectiveness of a nutrition assistant role in a head and neck cancer clinic. Kiss N, Gilliland S, Quinn P, Atkins L, Black J, Frowen J. Nutr Diet. 2018 Aug 16. [Epub ahead of print]

Implementing and sustaining an evidence-based nutrition service in a haematology unit for autologous stem cell transplant patients. Atkins L, Steer B, Ray H, Kiss N. Support Care Cancer. 2018 Aug 2. [Epub ahead of print]

Supplemental prophylactic intervention for chemotherapy-induced nausea and emesis (SPICE) trial: Protocol for a multicentre double-blind placebo-controlled randomised trial. Marx W, McCarthy A, Marshall S, Crichton M, Molassiotis A, Ried K, Bird R, Lohning A, Isenring E. Nutr Diet. 2018 Jul 23. [Epub ahead of print]

Cancer cachexia: Diagnosis, assessment, and treatment. Sadeghi M, Keshavarz-Fathi M, Baracos V, Arends J, Mahmoudi M, Rezaei N. Crit Rev Oncol Hematol. 2018 Jul;127:91-104. Review.

How to feed patients with gastrointestinal mucositis. Arends J. Curr Opin Support Palliat Care. 2018 Jun;12(2):168-173.

An investigation into the nutritional status of patients receiving an Enhanced Recovery After Surgery (ERAS) protocol versus standard care following Oesophagectomy. Benton K, Thomson I, Isenring E, Mark Smithers B, Agarwal E. Support Care Cancer. 2018 Jun;26(6):2057-2062.

Prevalence of malnutrition and impact on clinical outcomes in cancer services: A comparison of two time points. Marshall KM, Loeliger J, Nolte L, Kelaart A, Kiss NK. Clin Nutr. 2018 May 2. [Epub ahead of print]

Systematic review and meta-analysis of the evidence for oral nutritional intervention on nutritional and clinical outcomes during chemo(radio)therapy: current evidence and guidance for design of future trials. de van der Schueren MAE, Laviano A, Blanchard H, Jourdan M, Arends J, Baracos VE. Ann Oncol. 2018 May 1;29(5):1141-1153.

Is telehealth effective in managing malnutrition in community-dwelling older adults? A systematic review and meta-analysis. Marx W, Kelly JT, Crichton M, Craven D, Collins J, Mackay H, Isenring E, Marshall S. Maturitas. 2018 May;111:31-46. Review.

Does Modality Matter? Palliative Care Unit Associated With More Cost-Avoidance Than Consultations. May P, Garrido MM, Del Fabbro E, Noreika D, Normand C, Skoro N, Cassel JB. J Pain Symptom Manage. 2018 Mar;55(3):766-774.

Partnering with families to promote nutrition in cancer care: feasibility and acceptability of the PIcNIC intervention. Molassiotis A, Roberts S, Cheng HL, To HKF, Ko PS, Lam W et al. BMC Palliat Care. 2018 Mar 20;17(1):50. Free PMC Article

Struggling with nutrition in patients with advanced cancer: nutrition and nourishment-focusing on metabolism and supportive care. Arends J. Ann Oncol. 2018 Feb 1;29(suppl_2):ii27-ii34.

Practical approaches to managing cancer patients with weight loss. Del Fabbro E, Orr TA, Stella SM. Curr Opin Support Palliat Care. 2017 Dec;11(4):272-277.

Immune-Enhancing Formulas for Patients With Cancer Undergoing Esophagectomy: Systematic Review Protocol. Naranjo A, Isenring E, Teleni L. JMIR Res Protoc. 2017 Nov 17;6(11):e214.

ESPEN expert group recommendations for action against cancer-related malnutrition. Arends J, Baracos V, Bertz H, Bozzetti F, Calder PC, Deutz NEP et al. Clin Nutr. 2017 Oct;36(5):1187-1196. Review.

The applicability of a weight loss grading system in cancer cachexia: a longitudinal analysis. Vagnildhaug OM, Blum D, Wilcock A, Fayers P, Strasser F, Baracos VE et al; European Palliative Care Cancer Symptom study group. J Cachexia Sarcopenia Muscle. 2017 Oct;8(5):789-797.

The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial. Marx W, McCarthy AL, Ried K, McKavanagh D, Vitetta L, Sali A, Lohning A, Isenring E. Nutrients. 2017 Aug 12;9(8). Free PMC Article

[Nutrition in Cancer: Effective in Prevention and Treatment?] Arends J. Dtsch Med Wochenschr. 2017 Jun;142(12):889-895. Review. German

Nutrition interventions in patients with gynecological cancers requiring surgery. Obermair A, Simunovic M, Isenring L, Janda M. Gynecol Oncol. 2017 Apr;145(1):192-199. Review.

ESPEN guidelines on nutrition in cancer patients. Arends J, Bachmann P, Paracos V, Barthelemy N, Bertz H et al. Clin Nutr. 2017 Feb;36(1):11-48.

Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling. Pettersen K, Andersen S, Degen S, Tadini V, Grosjean J, Hatakeyama S et al. Sci Rep. 2017 May;7(1):2046. Free Full Text

Weight loss versus muscle loss: re-evaluating inclusion criteria for future cancer cachexia interventional trials. Roeland EJ, Ma JD, Nelson SH, Seibert T, Heavey S, Revta C et al. Support Care Cancer. 2017 Feb;25(2):365-369.

New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss. Johns N, Stretch C, Tan BH, Solheim TS, Sørhaug S, Stephens NA et al. J Cachexia Sarcopenia Muscle. 2017 Feb;8(1):122-130. Epub 2016 Aug 5. Free Full Text

The Evolving Approach to Management of Cancer Cachexia. Dev R, Wong A, Hui D, Bruera E. Oncology (Williston Park). 2017 Jan 15;31(1):23-32. Review.  Free Full Text

Cancer Cachexia: It Takes a Team to Fix the Complex Machinery. Hui D. J Oncol Pract. 2016 Nov;12(11):1172-1173.

Cancer Cachexia: Beyond Weight Loss. Bruggeman AR, Kamal AH, LeBlanc TW, Ma JD, Baracos VE, Roeland EJ. J Oncol Pract. 2016 Nov;12(11):1163-1171.

Early and Intensive Dietary Counseling in Lung Cancer Patients Receiving (Chemo)Radiotherapy-A Pilot Randomized Controlled Trial. Kiss N, Isenring E, Gough K, Wheeler G, Wirth A, Campbell BA, Krishnasamy M. Nutr Cancer. 2016 Aug-Sep;68(6):958-67. 

Gaps in nutritional research among older adults with cancer. Presley CJ, Dotan E, Soto-Perez-de-Celis E, Jatoi A, Mohile SG, Won E, et al. J Geriatr Oncol. 2016 Jul;7(4):281-92. Review. Free Full Text

Chemotherapy-Induced Nausea and Vomiting: A Narrative Review to Inform Dietetics Practice. Marx W, Kiss N, McCarthy AL, McKavanagh D, Isenring L. J Acad Nutr Diet. 2016 May;116(5):819-27. Review.

Clinical results in cachexia therapeutics. Crawford J. Curr Opin Clin Nutr Metab Care. 2016 May;19(3):199-204. Review.

"ScreenIT": Computerized screening of swallowing, nutrition and distress in head and neck cancer patients during (chemo)radiotherapy. Wall LR, Cartmill B, Ward EC, Hill AJ, Isenring E, Byrnes J et al. Oral Oncol. 2016 Mar;54:47-53.

Pretreatment depression as a prognostic indicator of survival and nutritional status in patients with head and neck cancer. Verdonck-de Leeuw IM, Cuijpers P, Leemans CR. Cancer. 2016 Mar 15;122(6):971-2.

Nutrition support and dietary interventions for patients with lung cancer: current insights. Kiss N. Lung Cancer (Auckl). 2016 Jan 27;7:1-9. eCollection 2016. Review.

The last days of life: symptom burden and impact on nutrition and hydration in cancer patients. Hui D, Dev R, Bruera E. Curr Opin Support Palliat Care. 2015 Dec;9(4):346-54. Review. Free Full Text

The eating experience after treatment for head and neck cancer: A review of the literature. Ganzer H, Touger-Decker R, Byham-Gray L, Murphy BA, Epstein JB. Oral Oncol. 2015 Jul 51(7):634-42. Review.

Dietary experiences and support needs of women who gain weight following chemotherapy for breast cancer. Kwok A, Palermo C, Boltong A. Support Care Cancer. 2015 Jun;23(6):1561-8.

Development of a lack of appetite item bank for computer-adaptive testing (CAT). Thamsborg LH, Petersen MA, Aaronson NK, Chie WC, Costantini A, Holzner B et al. Groenvold M; EORTC Quality of Life Group. Support Care Cancer. 2015 Jun;23(6):1541-8.

Which screening method is appropriate for older cancer patients at risk for malnutrition? Isenring E, Elia M. Nutrition. 2015 Apr;31(4):594-7.

Diagnostic criteria for the classification of cancer-associated weight loss. Martin L, Senesse P, Gioulbasanis I, Antoun S, Bozzetti F, Deans C, Strasser F et al. J Clin Oncol. 2015 Jan 1;33(1):90-9. Erratum in: J Clin Oncol. 2015 Mar 1;33(7):814.

Dosimetric factors associated with weight loss during (chemo)radiotherapy treatment for lung cancer. Kiss N, Krishnasamy M, Everitt S, Gough K, Duffy M, Isenring E. Eur J Clin Nutr. 2014 Dec;68(12):1309-14.

The prevalence of weight loss during (chemo)radiotherapy treatment for lung cancer and associated patient- and treatment-related factors. Kiss N, Isenring E, Gough K, Krishnasamy M. Clin Nutr. 2014 Dec;33(6):1074-80.

Immunomodulatory agents for the treatment of cachexia. Chasen M, Bhargava R, Hirschman S. Curr Opin Support Palliat Care. 2014 Dec;8(4):328-33.

Development of a multivariable normal tissue complication probability (NTCP) model for tube feeding dependence after curative radiotherapy/chemo-radiotherapy in head and neck cancer. Wopken K, Bijl HP, van der Schaaf A, van der Laan HP, Chouvalova O, Steenbakkers RJ et al. Radiother Oncol. 2014 Oct;113(1):95-101. 

Autonomic dysfunction in cancer cachexia coincides with large fiber polyneuropathy. Hundsberger T, Omlin A, Haegele-Link S, Vehoff J, Strasser F. J Pain Symptom Manage. 2014 Oct;48(4):611-8.e1.

Body composition following stem cell transplant: comparison of bioimpedance and air-displacement plethysmography. Hung YC, Bauer JD, Horsely P, Ward LC, Bashford J, Isenring EA. Nutrition. 2014 Sep;30(9):1000-6.

Dietary treatment of weight loss in patients with advanced cancer and cachexia: a systematic literature review. Balstad TR, Solheim TS, Strasser F, Kaasa S, Bye A. Crit Rev Oncol Hematol. 2014 Aug;91(2):210-21.

A novel, automated nutrition screening system as a predictor of nutritional risk in an oncology day treatment unit (ODTU). Abbott J, Teleni L, McKavanagh D, Watson J, McCarthy A, Isenring E. Support Care Cancer. 2014 Aug;22(8):2107-12.

Early recognition of malnutrition and cachexia in the cancer patient: a position paper of a European School of Oncology Task Force. Aapro M, Arends J, Bozzetti F, Fearon K, Grunberg SM, Herrstedt J, Hopkinson J, Jacquelin-Ravel N, Jatoi A, Kaasa S, Strasser F; ESMO (European School of Medical Oncology). Ann Oncol. 2014 Aug;25(8):1492-9.

Validation of the Consensus-Definition for Cancer Cachexia and evaluation of a classification model--a study based on data from an international multicentre project (EPCRC-CSA). Blum D, Stene GB, Solheim TS, Fayers P, Hjermstad MJ, Baracos VE, Fearon K, Strasser F, Kaasa S; Euro-Impact. Ann Oncol. 2014 Aug;25(8):1635-42.

A prospective cohort study of the effects of adjuvant breast cancer chemotherapy on taste function, food liking, appetite and associated nutritional outcomes. Boltong A, Aranda S, Keast R, Wynne R, Francis PA, Chirgwin J, Gough K. PLoS One. 2014 Jul 31;9(7):e103512.

Challenges and outcomes of a randomized study of early nutrition support during autologous stem-cell transplantation. Kiss N, Seymour JF, Prince HM, Dutu G. Curr Oncol. 2014 Apr;21(2):e334-9. Free Full Text

Patient satisfaction with nutrition services amongst cancer patients treated with autologous stem cell transplantation: a comparison of usual and extended care. Hung YC, Bauer J, Horsley P, Isenring E. J Hum Nutr Diet. 2014 Apr;27 Suppl 2:333-8.

Development and validation of a prediction model for tube feeding dependence after curative (chemo-) radiation in head and neck cancer. Wopken K, Bijl HP, van der Schaaf A, Christianen ME, Chouvalova O, Oosting SF et al. PLoS One. 2014 Apr 15;9(4):e94879. Free Full Text

The effect of nutrition intervention in lung cancer patients undergoing chemotherapy and/or radiotherapy: a systematic review. Kiss NK, Krishnasamy M, Isenring EA. Nutr Cancer. 2014;66(1):47-56.

Nutritional counseling and nutritional supplements: a cornerstone of multidisciplinary cancer care for cachectic patients. Isenring EA, Teleni L. Curr Opin Support Palliat Care. 2013 Dec;7(4):390-5.

Clinical outcomes of vitamin D deficiency and supplementation in cancer patients. Teleni L, Baker J, Koczwara B, Kimlin MG, Walpole E, Tsai K, Isenring EA. Nutr Rev. 2013 Sep;71(9):611-21.

Nutrition and exercise interventions for patients with lung cancer appear beneficial, but more studies are required. Kiss N, Isenring E. Curr Oncol. 2013 Aug;20(4):e281-2. Free Full Text

Changes in nutritional status, body composition, quality of life, and physical activity levels of cancer patients undergoing autologous peripheral blood stem cell transplantation. Hung YC, Bauer J, Horsley P, Waterhouse M, Bashford J, Isenring E. Support Care Cancer. 2013 Jun;21(6):1579-86.

Rapid EPA and DHA incorporation and reduced PGE2 levels after one week intervention with a medical food in cancer patients receiving radiotherapy, a randomized trial. Faber J, Berkhout M, Fiedler U, Avlar M, Witteman BJ, Vos AP, Henke M, Garssen J, van Helvoort A, Otten MH, Arends J. Clin Nutr. 2013 Jun;32(3):338-45.

A fishy conclusion regarding n-3 fatty acid supplementation in cancer patients. Murphy RA, Clandinin MT, Chu QS, Arends J, Mazurak VC. Clin Nutr. 2013 Jun;32(3):466-7.

Ability of existing malnutrition screening tools to identify risk of starvation, sarcopenia and cachexia: A systematic review. Healy, E., Yaxley, A., Isenring, E., Bannerman, E., & Miller, M. (2014). ESPEN Journal, 2014 9(3).